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Radiation Induced Cell Death in Cervical Squamous Cell Carcinoma : An Immunohistochemical and Ultrastructural Study
http://hdl.handle.net/10069/16103
http://hdl.handle.net/10069/16103f2930736-5845-4e23-998f-e60d903eaa83
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
acta43_01_07_t.pdf (2.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-03-13 | |||||
| タイトル | ||||||
| タイトル | Radiation Induced Cell Death in Cervical Squamous Cell Carcinoma : An Immunohistochemical and Ultrastructural Study | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cervical squamous cell carcinoma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cell death | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | TNF-alpha | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | TNF-receptor | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Atari, Eio
× Atari, Eio× Toda, Takayoshi× Muktafisadi, Al× Egawa, Haruhiko× Moromizat, Hidehiko× Mamadi, Touye× Kiyuna, Masaya |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To study the process of cell death in cervical squamous cell carcinoma (SCC) after radiation, an ultrastructural and immunohistochemical study was performed. Paraffinembedded tissue blocks of biopsy samples pre- and postradiation stage III SCC (n = 15) were collected. Irradiation caused varying ultrastructural changes including nuclear and cytoplasmic disorganization suggesting cell necrosis. Immunohistochemically, the pre-radiation specimens showed no positive reaction for tumor necrosis factor-alpha (TNF- ﾎｱ),tumor necrosis factor-receptor(TNF-ﾎｳ)or Fas. C-fos, p 53 and bcl-2 showed positive reactions in only a few nonirradiated specimens. All of the irradiated specimens showed a positive reaction for TNF-ﾎｱ,and variable positive reactions were observed for TNF-ﾎｳ,Fas, p 53, c-fos and bcl-2. These results suggest that TNF-ﾎｱ,TNF-ﾎｳ,and c-fos are responsible for radiation induced cell death in cervical SCC. | |||||
| 書誌情報 |
Acta medica Nagasakiensia 巻 43, 号 1-2, p. 38-43, 発行日 1998-06-30 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| sortkey | ||||||
| 値 | P00038-P00043 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia. 1998, 43(1-2), p.38-43 | |||||
